Some of the most common skin disease with systemic characterize is called dermatomyositis (DM). The basic changes appearing in individual with dermatomyositis are violaceous (heliotrope) inflammatory changes of the eyelids and periorbital area; erythema of the face, neck, and upper trunk; and flat-topped violaceous papules over the knuckles. It is associated with a polymyositis, interstitial pneumonitis, myocardial involvement, and vasculitis.
Dermatomyositis is considered one of the connective tissue diseases, like systemic sclerosis and lupus erythematosus. Why dermatomyositis occurs remains unknown but research is taking place to identify factors that may play a part in its development, some of which are listed below.
- Genetic predisposition
- Infectious or toxic agents acting as triggers
- Underlying cancer (more likely in the elderly)
The most common signs and symptoms of dermatomyositis include:
- Butterfly rash
- Skin redness or inflammation
- Red, dusky skin rash
- The rash may also affect cheeks, nose, shoulders, upper chest and elbows
- A scaly scalp and thinned out hair may occur